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(24) have a short while ago elevated a caveat towards the assertion that ADP is definitely an archaeal DNA ligase substrate by suggesting that contamination of the recombinant archaeal ligase protein preparations with the evidently thermostable E. coli

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S3), still the topology with the LigA clamp is starkly diverse from that in the clamps formed by ChVLig and HuLig1. The kissing contacts that shut the LigA clamp are sui generis

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